Cycobalamin bụ otu n'ime ogige vitamin B, nke nwere mmetụta mgbochi ọrịa anaemia siri ike. Ọ bụ aha e nyere site na kristal nke vitamin B12, ihe dị mkpa maka mmepe nke nje bacteria na anụmanụ. E wezụga C, H, O, N, P na Co, aDribose conjugate nke 5,6-dimethe-rbenzimidazole bụ akụkụ nke nhazi ya. AR Todd et al. tinye usoro nhazi, nke a na-akpọ cyanocobalamin n'ihi na a na-ahazi cyano na cobalt. Oke kachasị na ngwọta mmiri bụ 278,361,548 nm. Na 1948, E.L. Rickes nke United States na E.L. Smith nke United Kingdom weputara kristal n'onwe ya na imeju. Kemgbe ahụ, a na-enwetakwa ihe a site na ụfọdụ actinomycete (StrePtomyces griseum). Cyanocobalamin bụkwa ihe na-ebupụta ezì na ọkụkọ, ọ bụkwa otu ihe ahụ dị ka protein anụmanụ dị mkpa maka ịkụ akwa. Vitamin B12, nyere ndị ọrịa nwere ọrịa ọjọọ na 150 micrograms, nwere ike ịbawanye mkpụrụ ndụ ọbara uhie ihe dị ka ugboro abụọ, na 3-6 micrograms nwekwara ike ịmepụta mmetụta. Na vivo, a na-ebuga ya n'ọbara n'ụdị ngwakọta na protein trans-cobalamin (protein a-globular), ma dị n'ụdị coenzyme n'ụdị anụ ahụ dị iche iche. Yana folic acid, ọ na-etinye aka na metabolism nke mbufe methyl na ọgbọ methyl na-arụ ọrụ. Ma bụrụ ihe dị mkpa nke purine, pyrimidine na biosynthesis ndị ọzọ.
